The Farncombe Family Axenic-Gnotobiotic Facility at McMaster University offers a state-of-the-art, germ-free environment for studying host-microbial interactions. Since 2007, it has provided axenic mice, long-term experimental capabilities, and sterility for biomedical research. Services include breeding, tissue procurement, and re-derivation of mouse strains in controlled conditions, with advanced isolators and flexible film systems for specific experimental needs.