Human trials are set to begin early next year at an Ontario university for two next-generation COVID-19 vaccines that can be inhaled.
Fiona Smaill is a professor of pathology and molecular medicine at McMaster University in Hamilton and lead researcher for the clinical trials. She said on Tuesday that both vaccines, which would be the first inhaled vaccines, are “approved for study in Canada.” They’re designed to combat variants of concern and are delivered by inhaled aerosol, targeting the lungs and upper airways, where respiratory infections begin.
“The novel part of our vaccine is that we’re administering it by inhaled aerosol, and so the immune response that is generated in the lungs,” Smaill told CBC Hamilton.
“Not only do we have the vector that is unique, but we also have the route of administration and the generation of what we call a mucosal immunity, which we believe is a very effective form of immunity against respiratory viruses like COVID.”
Read the full CBC article here